{"id":24031,"date":"2026-10-13T12:49:08","date_gmt":"2026-10-13T10:49:08","guid":{"rendered":"https:\/\/biatgroup.com\/zip-solutions-advances-click-car-towards-future-leukaemia-therapies%ef%bf%bc\/"},"modified":"2026-10-13T12:52:52","modified_gmt":"2026-10-13T10:52:52","slug":"zip-solutions-advances-click-car-towards-future-leukaemia-therapies%ef%bf%bc","status":"publish","type":"post","link":"https:\/\/biatgroup.com\/es\/zip-solutions-advances-click-car-towards-future-leukaemia-therapies%ef%bf%bc\/","title":{"rendered":"ZIP Solutions avanza con Click-CAR hacia futuras terapias frente a leucemias"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"24031\" class=\"elementor elementor-24031 elementor-24027\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-453c6f5 elementor-section-boxed elementor-section-height-default elementor-section-height-default parallax_section_no qode_elementor_container_no\" data-id=\"453c6f5\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0461a8d\" data-id=\"0461a8d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-826a9f4 elementor-widget elementor-widget-text-editor\" data-id=\"826a9f4\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.11.5 - 14-03-2023 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#818a91;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#818a91;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<span data-contrast=\"auto\">ZIP Solutions, filial del grupo BIAT (BME ticker BST), ha publicado recientemente en la revista <\/span><i><span data-contrast=\"auto\">Frontiers in Immunology<\/span><\/i><span data-contrast=\"auto\"> una investigaci\u00f3n que aporta una prueba de concepto <\/span><i><span data-contrast=\"auto\">in vitro<\/span><\/i><span data-contrast=\"auto\"> para el desarrollo de Click-CAR. Esta tecnolog\u00eda propone construir receptores quim\u00e9ricos de ant\u00edgeno (CAR) a partir de m\u00f3dulos separados, con el objetivo de explorar nuevas formas de regular la actividad de las terapias celulares.<\/span><span data-ccp-props=\"{&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559738&quot;:300}\">\u00a0<\/span>\r\n\r\n<span data-contrast=\"auto\">El sistema combina una estructura de se\u00f1alizaci\u00f3n anclada al linfocito T con un adaptador que reconoce la diana tumoral. Usando las inte\u00ednas patentadas por ZIP Solutions, ambos componentes se unen para formar un receptor funcional. En este estudio, el adaptador se dirige a CD1a, un ant\u00edgeno presente en determinadas leucemias linfobl\u00e1sticas agudas de c\u00e9lulas T. Los ensayos mostraron actividad citot\u00f3xica espec\u00edfica frente a c\u00e9lulas leuc\u00e9micas CD1a positivas.<\/span><span data-ccp-props=\"{&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559738&quot;:300}\">\u00a0<\/span>\r\n\r\n<span data-contrast=\"auto\">El trabajo cuenta adem\u00e1s con investigadores del Instituto de Investigaci\u00f3n contra la Leucemia Josep Carreras, OneChain Immunotherapeutics, la Universitat Internacional de Catalunya y la Universidad de Roma Tor Vergata, as\u00ed como TERAV+, CIBERONC, la Universitat de Barcelona, ICREA y el entorno investigador Sant Joan de D\u00e9u\u2013Pediatric Cancer Center Barcelona, combinando excelencia en capacidades de ingenier\u00eda de prote\u00ednas, investigaci\u00f3n en leucemia y desarrollo de inmunoterapias celulares.<\/span><span data-ccp-props=\"{&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559738&quot;:300}\">\u00a0<\/span>\r\n\r\n<span data-contrast=\"auto\">Para Click-CAR, los resultados respaldan la viabilidad del ensamblaje mediante un adaptador externo y abren una v\u00eda para investigar el control temporal de la disponibilidad del receptor.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-ccp-props=\"{&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559738&quot;:300}\">\u00a0<\/span>\r\n\r\n<span data-contrast=\"auto\">Fuente: https:\/\/doi.org\/10.3389\/fimmu.2026.1844972<\/span><span data-ccp-props=\"{&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559738&quot;:300}\">\u00a0<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>La filial del grupo BIAT (BME ticker BST) ha publicado un estudio que demuestra el ensamblaje modular de c\u00e9lulas CAR-T. Los resultados respaldan el desarrollo de Click-CAR para futuras terapias frente a leucemias linfobl\u00e1sticas agudas de c\u00e9lulas T que expresan CD1a. <\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"content-type":"","om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_uf_show_specific_survey":0,"_uf_disable_surveys":false},"categories":[180],"tags":[],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.9 - aioseo.com -->\n\t<meta name=\"description\" content=\"La filial del grupo BIAT (BME ticker BST) ha publicado un estudio que demuestra el ensamblaje modular de c\u00e9lulas CAR-T. Los resultados respaldan el desarrollo de Click-CAR para futuras terapias frente a leucemias linfobl\u00e1sticas agudas de c\u00e9lulas T que expresan CD1a.\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<meta name=\"author\" content=\"Cristina Infante\"\/>\n\t<meta name=\"google-site-verification\" content=\"7GdH4l7ycE-EkTnk0wwEvyj0AHmR-FwhC4F7xBZV58w\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/biatgroup.com\/es\/zip-solutions-advances-click-car-towards-future-leukaemia-therapies%ef%bf%bc\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO (AIOSEO) 4.9.9\" \/>\n\t\t<meta property=\"og:locale\" content=\"es_ES\" \/>\n\t\t<meta property=\"og:site_name\" content=\"Biat Group - Biotecnolog\u00eda andaluza cotizada en BME MAB \u00b7 Ticker BST\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"ZIP Solutions avanza con Click-CAR hacia futuras terapias frente a leucemias - Biat Group\" \/>\n\t\t<meta property=\"og:description\" content=\"La filial del grupo BIAT (BME ticker BST) ha publicado un estudio que demuestra el ensamblaje modular de c\u00e9lulas CAR-T. 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Los resultados respaldan el desarrollo de Click-CAR para futuras terapias frente a leucemias linfobl\u00e1sticas agudas de c\u00e9lulas T que expresan CD1a.\" \/>\n\t\t<meta name=\"twitter:creator\" content=\"@BiatGroup\" \/>\n\t\t<meta name=\"twitter:image\" content=\"https:\/\/biatgroup.com\/wp-content\/uploads\/2022\/07\/logo-sin-fondo-Biatgroup.png\" \/>\n\t\t<script type=\"application\/ld+json\" class=\"aioseo-schema\">\n\t\t\t{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"BlogPosting\",\"@id\":\"https:\\\/\\\/biatgroup.com\\\/es\\\/zip-solutions-advances-click-car-towards-future-leukaemia-therapies%ef%bf%bc\\\/#blogposting\",\"name\":\"ZIP Solutions avanza con Click-CAR hacia futuras terapias frente a leucemias - Biat Group\",\"headline\":\"ZIP Solutions avanza con Click-CAR hacia futuras terapias frente a leucemias\",\"author\":{\"@id\":\"https:\\\/\\\/biatgroup.com\\\/es\\\/author\\\/biat-group\\\/#author\"},\"publisher\":{\"@id\":\"https:\\\/\\\/biatgroup.com\\\/es\\\/#organization\"},\"image\":{\"@type\":\"ImageObject\",\"url\":\"https:\\\/\\\/biatgroup.com\\\/wp-content\\\/uploads\\\/2022\\\/07\\\/logo-sin-fondo-Biatgroup.png\",\"@id\":\"https:\\\/\\\/biatgroup.com\\\/es\\\/#articleImage\",\"width\":516,\"height\":503},\"datePublished\":\"2026-10-13T12:49:08+02:00\",\"dateModified\":\"2026-10-13T12:52:52+02:00\",\"inLanguage\":\"es-ES\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/biatgroup.com\\\/es\\\/zip-solutions-advances-click-car-towards-future-leukaemia-therapies%ef%bf%bc\\\/#webpage\"},\"isPartOf\":{\"@id\":\"https:\\\/\\\/biatgroup.com\\\/es\\\/zip-solutions-advances-click-car-towards-future-leukaemia-therapies%ef%bf%bc\\\/#webpage\"},\"articleSection\":\"Splittera \\u00b7 ZIP Solutions, Opcional\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/biatgroup.com\\\/es\\\/zip-solutions-advances-click-car-towards-future-leukaemia-therapies%ef%bf%bc\\\/#breadcrumblist\",\"itemListElement\":[{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/biatgroup.com\\\/es\\\/#listItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/biatgroup.com\\\/es\\\/\",\"nextItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/biatgroup.com\\\/es\\\/category\\\/splittera-zip-es\\\/#listItem\",\"name\":\"Splittera \\u00b7 ZIP Solutions\"}},{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/biatgroup.com\\\/es\\\/category\\\/splittera-zip-es\\\/#listItem\",\"position\":2,\"name\":\"Splittera \\u00b7 ZIP Solutions\",\"item\":\"https:\\\/\\\/biatgroup.com\\\/es\\\/category\\\/splittera-zip-es\\\/\",\"nextItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/biatgroup.com\\\/es\\\/zip-solutions-advances-click-car-towards-future-leukaemia-therapies%ef%bf%bc\\\/#listItem\",\"name\":\"ZIP Solutions avanza con Click-CAR hacia futuras terapias frente a leucemias\"},\"previousItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/biatgroup.com\\\/es\\\/#listItem\",\"name\":\"Home\"}},{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/biatgroup.com\\\/es\\\/zip-solutions-advances-click-car-towards-future-leukaemia-therapies%ef%bf%bc\\\/#listItem\",\"position\":3,\"name\":\"ZIP Solutions avanza con Click-CAR hacia futuras terapias frente a leucemias\",\"previousItem\":{\"@type\":\"ListItem\",\"@id\":\"https:\\\/\\\/biatgroup.com\\\/es\\\/category\\\/splittera-zip-es\\\/#listItem\",\"name\":\"Splittera \\u00b7 ZIP Solutions\"}}]},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/biatgroup.com\\\/es\\\/#organization\",\"name\":\"Biotechnology Assets S.A. 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