Biobide CRO — Zebrafish Testing Services
Biobide — The Premier Zebrafish CRO
Accelerating R&D with Aquatic NAMs. High-fidelity in-vivo data. In-vitro speed. Zero regulatory animal burden.
Why Zebrafish NAMs
In-vivo data quality. In-vitro speed.
Zebrafish embryo models deliver whole-organism biological relevance with the scalability and speed of in-vitro methods. Under EU Directive 2024/1262, assays conducted on embryos prior to 120 hpf are classified as NAMs — zero animal welfare regulatory burden.
High Genetic Homology
Over 80% genetic similarity with humans. Systemic biological context unavailable in purely cellular models.
Speed & Throughput
Results in 2-4 weeks. High-throughput ready with standard microplate compatibility. 100-300 eggs per couple/week.
GLP Certified
Fully GLP-certified environment (ENAC 2026). Results accepted by regulatory agencies for preclinical studies.
Services by Industry
Tailored Solutions for Every Sector
Pharma & Biotech
DART screening. Based on OECD 236. EC50, LC50, Teratogenic Index, NOAEL.
Developmental Neurotoxicity (DNT). CNS disease modeling. DanioVision system.
Heart rate, arrhythmia and fibrillation analysis via proprietary Cardio software.
Acute opacity assessment, steatosis and histopathology.
Morphological changes in kidney development.
Based on OECD 236. Coagulation, somites, heartbeat and tail detachment.
Cosmetics & Personal Care
Safety by DesignEU Directive 2024/1262 and global consumer demands strictly prohibit animal testing for cosmetics. Biobide's EASZY assay provides the only Level 3 OECD-recognized whole-organism EDC screening without triggering animal testing regulations.
Estrogenic ER agonist screening. 100% accuracy, sensitivity and specificity.
Androgenic and antiandrogenic activity screening.
Estrogenic and antiestrogenic activity screening.
Thyroid hormone disruptor screening.
Thyroid gland disruptor screening.
Weight of Evidence dossiers. Safety by Design positioning.
Agrochemical, Chemical & Environmental
GLP CertifiedFully GLP-certified ecotoxicity testing for regulatory compliance. OECD test guidelines for industrial chemicals, biocides, plant protection products and food ingredients.
Fish Acute Toxicity (OECD TG 203), Early-Life Stage (TG 210), Fish Embryo FET (TG 236).
Acute Immobilization (OECD TG 202), Reproduction Test (TG 211).
Freshwater Alga Growth Inhibition (OECD TG 201).
Industrial Chemicals & REACH
Innate and adaptive immune system tracking (leukocyte infiltration, lymphopoiesis).
DASPEI staining to visualize and analyze neuromasts after 24h treatment.
Ad-hoc model generation, target validation and disease modeling.
Trusted by Global Industry Leaders
We partner with top pharmaceutical, biotech, agrochemical and cosmetic companies, alongside major regulatory agencies including NIH, L'Oréal, BASF, Corteva and DSM-Firmenich.
